Spike protein

Spike proteins, also known as peplomers, are the knoblike structures generally composed of glycoproteins, projecting from the lipid bilayer of the surface of an enveloped virus. Peplomers play important roles in the infection process; they are responsible for the attachment of the virus particle or virion to receptor sites on the host cell's surface, and bringing about the release of the nucleocapsid containing the virus's genetic material into the host cell's cytoplasm by triggering fusion between the envelope and host membranes. They may have hemagglutinating activity or have enzyme activity such as neuraminidase. They are surface antigens.


Spike proteins, also known as peplomers, are the knoblike structures generally composed of glycoproteins, projecting from the lipid bilayer of the surface of an enveloped virus. Peplomers play important roles in the infection process; they are responsible for the attachment of the virus particle or virion to receptor sites on the host cell's surface, and bringing about the release of the nucleocapsid containing the virus's genetic material into the host cell's cytoplasm by triggering fusion between the envelope and host membranes. They may have hemagglutinating activity or have enzyme activity such as neuraminidase. They are surface antigens.
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