Hiyama coupling

2020-06-09 12:06:08

The Hiyama coupling is a palladium-catalyzed cross-coupling reaction of organosilanes with organic halides used in organic chemistry to form carbon–carbon bonds. This reaction was discovered in 1988 by Tamejiro Hiyama and Yasuo Hatanaka as a method to form carbon-carbon bonds synthetically with chemo- and regioselectivity. The Hiyama coupling has been applied to the synthesis of various natural products. : aryl, alkenyl or alkynyl : aryl, alkenyl, alkynyl or alkyl : Cl, F or alkyl : Cl, Br, I or OTf

The Hiyama coupling is a palladium-catalyzed cross-coupling reaction of organosilanes with organic halides used in organic chemistry to form carbon–carbon bonds. This reaction was discovered in 1988 by Tamejiro Hiyama and Yasuo Hatanaka as a method to form carbon-carbon bonds synthetically with chemo- and regioselectivity. The Hiyama coupling has been applied to the synthesis of various natural products. : aryl, alkenyl or alkynyl : aryl, alkenyl, alkynyl or alkyl : Cl, F or alkyl : Cl, Br, I or OTf
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