Abamectin is a widely used insecticide and anthelmintic. Abamectin, is a member of the Avermectin family and is a natural fermentation product of soil dwelling actinomycete Streptomyces avermitilis. Abamectin, differs from Ivermectin, the popular member of the Avermectin family, by double bond on C-22-25. Fermentation of Streptomyces avermitilis yields 8 closely related Avermectin homologues out of which B1 forms the bulk of the fermentation. The non proprietary name, abamectin, is a combination of Bla and B1b. Out of all the Avermectins, abamectin is the only one that is used both in agriculture and pharmaceuticals.